Immun . Yan Ge and Yasuko Rikihisa chaffeensis Ehrlichia Surface - Exposed Proteins

Surface-exposed proteins of Ehrlichia chaffeensis.

The surface proteins of Ehrlichia chaffeensis provide an important interface for pathogen-host interactions. To investigate the surface proteins of E. chaffeensis, membrane-impermeable, cleavable Sulfo-NHS-SS-Biotin was used to label intact bacteria. The biotinylated bacterial surface proteins were isolated by streptavidin-agarose affinity purification. The affinity-captured proteins were separ...

The omp-1 major outer membrane multigene family of Ehrlichia chaffeensis is differentially expressed in canine and tick hosts.

Sixteen of 22 omp-1 paralogs encoding 28-kDa-range immunodominant outer membrane proteins of Ehrlichia chaffeensis were transcribed in blood monocytes of dogs throughout a 56-day infection period. Only one paralog was transcribed by E. chaffeensis in three developmental stages of Amblyomma americanum ticks before or after E. chaffeensis transmission to naïve dogs.

Ehrlichia chaffeensis Transcription Factors in Human Monocytes by Janus Kinases and Latent Cytoplasmic of Interferon-Induced Tyrosine Phosphorylation Protein Kinase A-Mediated Inhibition of Gamma

1 1 c - di - GMP Signaling Regulates Intracellular Aggregation , Sessility , 2 and Growth of Ehrlichia chaffeensis

Running title: E. chaffeensis morula and c-di-GMP 14 15 *Corresponding author. Mailing address: Department of Veterinary Biosciences, 16 College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, 17 Columbus, Ohio 43210-1093. Phone: (614) 292-9677. Fax: (614) 292-6473. E-mail: 18 [email protected]. 19 20 Current address: Research Institute for Microbial Diseases, Osaka Univer...

Ehrlichia chaffeensis Infection of Sika Deer, Japan

To determine whether Ehrlichia chaffeensis exists in Japan, we used PCR to examine blood from sika deer in Nara, Japan. Of 117 deer, 36 (31%) were infected with E. chaffeensis. The E. chaffeensis 16S rRNA base and GroEL amino acid sequences from Japan were most closely related to those of E. chaffeensis Arkansas.